Clinical Pulmonary Infection Score (CPIS)

CPIS helps estimate the likelihood that a ventilated patient has developed ventilator-associated pneumonia (VAP), combining clinical, radiographic, and lab findings into a single score.

Clinical Pulmonary Infection Score (CPIS)

CPIS
0
points · max 12
VAP less likely (≤ 6)

What the Score Means

≤ 6

VAP less likely — reconsider antibiotics.

> 6

VAP more likely — supports antibiotic therapy pending cultures.

Frequently Asked Questions

Is CPIS used to definitively diagnose VAP?

No — it's a bedside estimation tool to help decide whether to start or continue antibiotic therapy while awaiting definitive culture results, not a standalone diagnostic test.

What CPIS suggests VAP?

A score above 6 suggests ventilator-associated pneumonia is more likely. Below that, VAP is less likely and antibiotics may be reconsidered.

Why include oxygenation (PF ratio)?

Worsening oxygenation not explained by ARDS suggests new lung consolidation, one of the signals that a ventilated patient may have developed pneumonia.

What are the limits of CPIS?

Its accuracy is modest and interobserver variability exists, so it supplements — rather than replaces — clinical judgment and microbiology.

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